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WEDNESDAY, May 20, 2015 (HealthDay News) -- Undergoing chemotherapy before surgery may help women battling advanced ovarian cancer, a new study finds.

The British study was led by Sean Kehoe, professor of gynecological cancer at the University of Birmingham, and included 550 patients. About half underwent the standard treatment of surgery followed by six cycles of chemotherapy, while the other half had three cycles of chemotherapy before their surgery.

The risk of complications and death within 28 days after surgery was lower among those who had chemotherapy before surgery, Kehoe's team found. They also had fewer side effects, spent less time in the hospital, and experienced a better quality of life, the findings showed.

The study was funded by Cancer Research U.K. and was published May 19 in The Lancet.

"Whether to have chemotherapy before major surgery for ovarian cancer has always been a dilemma for women and their surgeons," Peter Johnson, chief clinician at Cancer Research U.K., said in a news release from the organization.

"Thanks to this study, we can say that having chemotherapy first makes the surgery safer, the stay in hospital shorter, and women's quality of life better," he said.

Study lead author Kehoe agreed. "The trial showed that shrinking the tumor [with chemotherapy] before surgery reduced side effects and hospital stay -- meaning improved quality of life, without compromising survival, which is better for patients," he said in the news release.

According to the American Cancer Society, ovarian cancer remains one of the deadliest cancer types. The society estimates that in 2015, more than 21,000 American women will be diagnosed with the disease, and more than 14,000 women will die from it. Ovarian cancer is the fifth biggest cancer killer of women overall, the group says.

-- Robert Preidt
Copyright © 2015 HealthDay. All rights reserved.SOURCE: Cancer Research U.K., news release, May 19, 2015

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MedicationsSupplements and Vitamins home > healthy kids center > healthy kids a-z list > clowning around good medicine for surgery article

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FRIDAY, May 15, 2015 (HealthDay News) -- If laughter is the best medicine, that may be doubly true for kids undergoing surgery who were cheered up by visiting clowns, a new Israeli study suggests.

This study included children ages 2 to 16 undergoing outpatient urologic surgery at Shaare Zedek Medical Center in Jerusalem. The children were divided into two groups -- in one group, the surgical team included a "medical clown" in the operating room to help entertain the kids.

The results suggest a funny intervention can make a serious impact on kids' well-being: The clown's antics were tied to less anxiety for kids before and after surgery, less time in the operating room, lower levels of pain, and shorter time to discharge from the hospital, the study found.

There was even a financial bonus: Related reductions in surgery and recovery time led to a cost savings of more than $461 per patient, the researchers said. The study, by researcher Stanislav Kocherov, was to be presented Friday at the annual meeting of the American Urological Association (AUA), in New Orleans.

"These data clearly demonstrate the unique role medical clowns play in reducing anxiety among children in an outpatient surgery setting as well as the amount of time spent in the hospital, which subsequently may lead to lower hospital costs," AUA spokesman Dr. Anthony Atala, director of the Wake Forest Institute for Regenerative Medicine, said in an AUA news release.

While the study results should be considered preliminary until published in a peer-reviewed journal, two other experts in the United States agreed that laughter may have the power to help sick kids.

"This study makes sense to me -- few things could be more distracting and amusing than a funny clown," said Dr. Saidi Clemente, director of pediatric development at Staten Island University Hospital in New York City. "We pediatricians have known for a long time that distraction techniques reduce anxiety prior to medical procedures, such as blood drawing for example."

Another doctor said he's seen the intervention work, first-hand.

"We have had clowns visit our patients on the pediatric ward at Northern Westchester Hospital," said Dr. Peter Richel, who is chief of pediatrics at the hospital located in Mount Kisco, N.Y. "Clearly, when the clowns arrive, they generate a feeling of good will, happiness, and compassion with their humor, all of which add to a speedier recovery for our children. There is a tremendous benefit from clowning around."

In fact, the Israeli team noted that dozens of medical clown "guilds" -- inspired by the clownish "Patch Adams" character created by Robin Williams in the movie of the same name -- have been established at hospitals in the United States, Canada and Europe over the past few decades.

-- Robert Preidt
Copyright © 2015 HealthDay. All rights reserved.SOURCES: Saidi Clemente, M.D., director of pediatric developmental behavior, Staten Island University Hospital, New York City; Peter Richel, M.D., chief of pediatrics, Northern Westchester Hospital, Mount Kisco, N.Y.; American Urological Association, news release, May 15, 2015

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